Author Correction: Myocardial reprogramming by HMGN1 underlies heart defects in trisomy 21

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Under the Trump Administration, the Department of Defense has become much more vocal about the importance of investments in defense technology. It has also sometimes become combative with some of the companies it has contracted with. Last week, President Trump announced via Truth Social that federal agencies must stop working with the LLM company Anthropic, and Secretary of War Pete Hegseth later tweeted that he was directing the Pentagon to designate Anthropic a “supply-chain risk.”

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Dorsey made it clear that “the business is strong” and “intelligence tools” were changing the way they could work. When commenters pointed out the bloat he’d created during Covid, Dorsey admitted that he’d over-hired but said those issues were addressed two years ago. And he gave numbers, saying he’s targeting $2 million+ gross profit per person vs. $500,000 from 2019 to 2024. Leadership expert Stephen Miles calls the move “exceptionally executed,” and gives Dorsey kudos for courage, arguing that “the amount of self-belief he has that the company can be even better with fewer people shows he’s not being ruthless, just brutally honest about what’s best for the future of the company.”